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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX59
All Species:
23.94
Human Site:
Y117
Identified Species:
35.11
UniProt:
Q5T1V6
Number Species:
15
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T1V6
NP_001026895.2
619
68810
Y117
V
C
G
R
Y
G
E
Y
I
C
D
K
T
D
E
Chimpanzee
Pan troglodytes
XP_001143546
619
68778
Y117
V
C
G
R
Y
G
E
Y
I
C
D
K
T
D
E
Rhesus Macaque
Macaca mulatta
XP_001109688
319
35696
Dog
Lupus familis
XP_537128
620
68704
Y118
V
C
G
R
Y
G
E
Y
I
C
D
K
T
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBN9
619
68216
Y117
V
C
G
R
Y
G
E
Y
I
C
D
K
T
D
E
Rat
Rattus norvegicus
Q66HG7
589
65047
Y117
V
C
G
R
Y
G
E
Y
I
C
D
K
T
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520980
538
59378
E110
S
K
T
Q
R
W
A
E
P
G
E
P
V
C
V
Chicken
Gallus gallus
XP_422189
625
69278
Y122
V
C
G
R
Y
G
E
Y
I
C
D
K
T
D
E
Frog
Xenopus laevis
NP_001106297
254
27959
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
H244
V
K
T
K
K
M
P
H
A
T
K
K
K
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09052
661
72313
E140
Y
E
N
E
D
G
D
E
R
R
G
R
L
D
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198909
620
68882
D139
L
A
P
E
Q
V
Q
D
I
R
N
E
A
I
V
Poplar Tree
Populus trichocarpa
XP_002320399
524
57616
E95
C
F
Y
V
R
D
S
E
S
P
L
T
S
D
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3EBD3
505
55199
V77
A
T
D
E
C
F
Y
V
R
D
P
G
S
S
S
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
L114
P
G
P
K
N
A
K
L
E
A
E
L
F
G
V
Red Bread Mold
Neurospora crassa
Q7SEL0
728
82594
T174
A
K
K
K
R
R
R
T
A
A
N
K
F
N
F
Conservation
Percent
Protein Identity:
100
99
51
89.8
N.A.
83.6
79.8
N.A.
61.8
72.3
30.2
22.3
N.A.
27.6
N.A.
N.A.
32.1
Protein Similarity:
100
99.8
51.3
93.3
N.A.
89.6
86.7
N.A.
71.5
84.3
35.3
37.3
N.A.
45.8
N.A.
N.A.
52.4
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
0
100
0
20
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
0
100
N.A.
100
100
N.A.
13.3
100
0
33.3
N.A.
26.6
N.A.
N.A.
33.3
Percent
Protein Identity:
40.7
N.A.
N.A.
38.1
26.3
26.9
Protein Similarity:
58
N.A.
N.A.
56.2
46.3
46.4
P-Site Identity:
6.6
N.A.
N.A.
0
0
6.6
P-Site Similarity:
20
N.A.
N.A.
6.6
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
7
0
0
0
7
7
0
13
13
0
0
7
0
0
% A
% Cys:
7
38
0
0
7
0
0
0
0
38
0
0
0
7
0
% C
% Asp:
0
0
7
0
7
7
7
7
0
7
38
0
0
50
0
% D
% Glu:
0
7
0
19
0
0
38
19
7
0
13
7
0
0
44
% E
% Phe:
0
7
0
0
0
7
0
0
0
0
0
0
13
0
7
% F
% Gly:
0
7
38
0
0
44
0
0
0
7
7
7
0
13
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
44
0
0
0
0
7
0
% I
% Lys:
0
19
7
19
7
0
7
0
0
0
7
50
7
0
0
% K
% Leu:
7
0
0
0
0
0
0
7
0
0
7
7
7
0
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
7
0
0
0
0
0
13
0
0
7
0
% N
% Pro:
7
0
13
0
0
0
7
0
7
7
7
7
0
0
0
% P
% Gln:
0
0
0
7
7
0
7
0
0
0
0
0
0
0
7
% Q
% Arg:
0
0
0
38
19
7
7
0
13
13
0
7
0
0
7
% R
% Ser:
7
0
0
0
0
0
7
0
7
0
0
0
13
7
7
% S
% Thr:
0
7
13
0
0
0
0
7
0
7
0
7
38
0
0
% T
% Val:
44
0
0
7
0
7
0
7
0
0
0
0
7
0
19
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
7
0
38
0
7
38
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _